50. Haibane Renmei
49. Excel Saga
48. Gravitation
47. Love Hina Christmas Special
46. Saikano
45. Project A-Ko
44. Fushigi Yugi season 1
43. Mobile Suit Gundam: Char's Counterattack
42. Saiyuki season 2
41. Cardcaptor Sakura (YAY!) second movie DVD
40. Inuyasha DVD 12
39. Animatrix
38. GTO box 1
37. Heat Guy J
36. Sailor Moon S
35. Dragon Ball Z Perfect Cell Saga
34. Ghost in the Shell, the movie
33. Azumanga Daioh
32. Witch Hunter Robin
31. Ranma 1/2 season 1
30. Macross Plus, the movie
29. Trigun
28. Interstella 5555
27. Hellsing
26. Urusei Yatsura: Beautiful Dreamer
25. Castel of Cagliostro
24. Wolf's Rain
23. Perfect Blue
22. Tenchi Muyo OVA
21. Revolutionary Girl Utena, the movie
20. Ninja Scroll
19. Castle in the Sky
18. Rahxephon
17. Vampire Hunter D: Bloodlust
16. Escaflowne
15. The End of Evangelion
14. Gundam SEED
13. Grave of the Fireflies
12. Berserk
11. Cowboy Bebop
10. Fruits Basket
9. Read or Die
8. Robotech Legacy: The Macross Saga
7. FLCL
6. Ghost in the Shell: Stand Alone Complex
5. His and Her Circumstances
4. Akira
3. Rurouni Kenshin: Legends of Kyoto
2. Spirited Away
And the number one anime series on DVD that every otaku must have is..*drum roll please*.......... (I'll give you three guesses what it is, and the first two don't count
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#1. Evangelion!!!!!!
and that's it. If I had made the list Cardcaptor Sakura would have been number 1, and Sailor Moon would have been in the top 10 at least.